On the final day of UEG Week 2026 in Barcelona, Egle Dieninyte talks to interventional EUS specialist Giuseppe Vanella (Milan) about the endoscopy research that stood out. Several of the strongest studies asked deliberately simple clinical questions.

Key discussion points

• The plenary trial on short-course antibiotics after adequate source control in cholangitis due to distal obstruction, and the selected population it applies to.
• A Dutch randomised trial comparing primary percutaneous suprapapillary metal stenting with ERCP in malignant hilar strictures, and why the comparison is not like-for-like.
• EUS-guided transmural drainage as a way to avoid crossing the tumour or papilla.
• Two Italian trials of underwater versus gas-assisted ESD.
• The “FOMO” of interventional EUS: training, volume and quality standards.